03531nam a22002537a 4500 D0001E000127 DOH 20201105100258.0 201105b ||||| |||| 00| 0 eng d Exercise and the heart : the good, the bad, and the ugly / Sanjay Sharma [and two others] The benefits of exercise are irrefutable. Individuals engaging in regular exercise have a favourable cardiovascular risk profile for coronary artery disease and reduce their risk of myocardial infarction by 50%. Exercise promotes longevity of life, reduces the risk of some malignancies, retards the onset of dementia, and is as considered an antidepressant. Most of these benefits are attributable to moderate exercise, whereas athletes perform way beyond the recommended levels of physical activity and constantly push back the frontiers of human endurance. The cardiovascular adaptation for generating a large and sustained increase in cardiac output during prolonged exercise includes a 10-20% increase in cardiac dimensions. In rare instances, these physiological increases in cardiac size overlap with morphologically mild expressions of the primary cardiomyopathies and resolving the diagnostic dilemma can be challenging. Intense exercise may infrequently trigger arrhythmogenic sudden cardiac death in an athlete harbouring asymptomatic cardiac disease. In parallel with the extraordinary athletic milieu of physical performances previously considered unachievable, there is emerging data indicating that long-standing vigorous exercise may be associated with adverse electrical and structural remodelling in otherwise normal hearts. Finally, in the current era of celebrity athletes and lucrative sport contracts, several athletes have succumbed to using performance enhancing agents for success which are detrimental to cardiac health. This article discusses the issues abovementioned, which can be broadly classified as the good, bad, and ugly aspects of sports cardiology. In: European Heart Journal, 2015 vol. 36 (23) pages: 1445–1453 Arrhythmias, Cardiac physiopathology Atrial Fibrillation etiology Atrial Fibrillation physiopathology Cardiomegaly, Exercise-Induced physiology Exercise physiology Heart Diseases prevention and control Sharma, Sanjay Merghani, Ahmed Mont, Lluis https://watermark.silverchair.com/ehv090.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAArEwggKtBgkqhkiG9w0BBwagggKeMIICmgIBADCCApMGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQM94zSMlhTiFw_Pt0IAgEQgIICZJKwBCfvCKHq-ZSrsN1QLm7kQ_4p4PdxyUY2-0-TSOMvXTqt5Z8zZ9fM4gOUOGM4JbD2NdiRrhhjVfeZ81vBUqqOExq8XX_c-oQ7f7rn7b42vONG5QXH8EIS-H6C5jK_N8SuXqhrUOlMS1VRiEaYWh0gUKOxyPTyhfVAvC3UCuoAwE4JQ-AMjdR8xG0iCk1QYZuFObg2_GaihFZ42BvjI13X829VPD6MOjF7lZqMqb-dd7R53SUlkbBiZHkO-ZWbuXhgL82X__q-txZo8N8A3aFn16XNXuu7YaWubw6YfmYmwvYllRIyMq3zuyFkOngzLjCjjKRBQPAqd23Q8CnDCkE8A0JUNNHWzKT1Eorc-vLwV-JSqeR5NtFq1fDLYER7JsSVcuR4xCf1hwwcJ_jOW9YidwhgHhG7m_vPe24-4pAC_KgRRwpHx6jYZNVq65q6TAyjV6rpIPBzKtipZn9ZNj72c80U0yz5tJsAhdBvPsAK_mqSzBMmEIwwlYZnltREfuu5scMVctdfztQk4GBkg7OjtL-iEjiWxjluWqu6nx5ZURC5QJEjv2XIw8T6TnkqXlsjQOG4InxqivLAe8vAqnX5_Qv0juTuWlmKLjubqFCX6HnuJcAP5tDEuC5xk5PWHKy1WhxeOZiVAW4u06DcHkvY4Zh1Sd1Ye5yeFkywdeU1SBf6_BR2Md5dO1CfNHXHfmq-tsij_TFV6a00Vld_GnHu0FNKiijWab1agSFtdGbvAeVzLk0TtPyO9O9VNVgpr7yCwoS_LsCEP7UGUX_RP-tF3_Uym2NJ1DrgitQHJUNngf4Y7Q JA 1645 1645 0 0 0 0 DOHCL DOHCL ElectronicRes 2020-11-05 0 E000127 D0001E000127 2020-11-05 00:00:00 2020-11-05 JA