02677nam a22004337a 4500001001300000003000400013005001700017008004100034245019500075520127800270580005501548650003001603650001001633650002101643700002901664700001901693700002801712700002501740700002401765700002901789700001901818700002501837700003101862700002501893700003401918700002601952700001801978700001701996700002902013700001802042700002002060700002802080700002402108700002402132700001902156700002102175700002302196700002402219D0001J000162DOH20210312161126.0210312b           ||||| |||| 00| 0 eng d00aSerum gamma-glutamyltransferase levels after an alcohol challenge in two groups of medical students with different average alcohol consumption /cLeilani Lucille Pichay [twenty three others]3 aOBJECTIVES: This study aimed to compare the serum GGT levels of alcohol drinkers and controls METHODOLOGY: Eighteen to 28 year old Filipino male medical students of the University of the Philippines College of Medicine were recruited to answer a self-administered questionnaire determining patterns of alcohol intake. The subjects were then classified as drinkers (drinks alcohol of 60-120 g ethanol) and controls (weekly consumption of not more than 0.57 g ethanol). Serum GGT levels were obtained at baseline, after 28 days of abstinence and after alcohol challenge RESULTS: The GGT levels of the two groups were similar at baseline. Analysis of variance revealed a possible interaction between the grouping and the period of observation. Using the 28 day abstinence values as baseline, there was a difference in the changes in the GGT levels between the two groups after alcohol challenge. The mean GGT value in the drinkers group increased by 3 U/L while the mean GGT value in the control group decreased by 1.6 U/L. This difference was statistically significant (p-value=0.0023) CONCLUSION: These findings showed that the alcohol challenge test can be a diagnostic tool in determining individuals who have regularly ingested alcohol within this studys specified range.  aActa Medica Philippina,1997 33 ( 3 ) pages 103-110 2agamma-Glutamyltransferase 2aSerum 2aAlcohol Drinking1 aPichay, Leilani Lucille 1 aTan, Jennifer 1 aFrancisco, Ma. Jennina 1 aPalileo, Lia Aileen 1 aTandoc, Neil Alvin 1 aEstrada, Dexter Francis 1 aMedina, Edgar 1 aSilva, Arvin Thomas 1 aDimaialuan, Conrad Narsil 1 aLibames, Nikki Rose 1 aStrebel, Heinrik Martin Jude 1 aZafra,  Mario Adrian 1 aDomingo, Dewi1 aLim, Melody 1 aSeverino, Oliver Gerald 1 aValte, David 1 aAlonzo, Marian 1 aLopez, Celeste Cheryll 1 aRonque, Peter Paul 1 aTecson, Ma. Pamela 1 aFeir, Sherwin 1 aQuijano, Dennis 1 aTan, Chuck Lester 1 aFontanilla, Regina