TY  - BOOK
AU  - Garcia,Robert Dennis J.
AU  - Sorra,Lemuel L.
TI  - A study comparing the profiles of nosocomial infection at the MMC-Pediatric Intensive Care Unit between the Pre-ISO 9002/EN 46002 and ISO 9002/EN 46002 Eras
KW  - Cross Infection
N2  - OBJECTIVE: To describe and compare the profiles of nosocomial infections (NI) at the Makati Medical Center - Pediatric Intensive Care Unit between the Pre-ISO 9002/EN 46002 Era (January 2000 - December 2010) and the ISO 9002/EN 46002 Era (April 2001 - March 2002).

DESIGN: Retrospective cohort study. Setting: Makati Medical Center - Pediatric Intensive Care Unit (MMC PICU) from January 2000 to December 2000 and April 2001 to March 2002.

PATIENTS/PARTICIPANTS: A total of 192 patients (94 from January 2000 to December 2000 and 98 from April 2001 to March 2002) admitted into the MMC PICU.

INTERVENTIONS: An extensive chart review was done on all admissions. Patient demographics, the number of PICU days, development of NI, microbiologic data, and site of infection were all noted. Common isolates were also noted.

MAIN OUTCOME MEASURES: Cumulative incidence and incidence densities of over-all NI, major specific site NI (i.e. primary bloodstream, pneumonia, UTI), and device-associated NI.

RESULTS: There is a slight insignificant decrease in the incidence rates of all NI from the Pre-ISO 9002/EN 46002 era to the ISO 9002/EN 46002 era with the exception of urinary tract infection which had an insignificant increase in rate. Device-associated NI also followed the same trend. Possible reasons and implications of such results are discussed. Common organisms isolated were listed, most common isolate being Pseudomonas spp. for the Pre-ISO 9002/EN 46002 era and Pseudomonas aeruginosa for the ISO 9002/EN 46002 era.

CONCLUSION: The profiles of NI in the Pre-ISO 9002/EN 46002 and in the ISO 9002/EN 46002 are comparable and exhibit minimal statistical differences. Both eras follow the same trend for major specific site NI as well as device-associated NI. With the exception of UTI, the slight insignificant decrease in incidence of NI in the two eras may indicate the beginning impact of the ISO certification. An increase in the length of transition period between the two eras is recommended for future evaluation studies. The increase in incidence of UTI between the two eras needs further investigation so that corrective actions may be undertaken. (Author)
ER  -