000			01548nam a22001937a 4500
001			D0001J000159
003			DOH
005			20210312143258.0
008			210312b ||||| |||| 00| 0 eng d
100	1		_aMontoya, Jaime C.
245	0	0	_aDiagnosis of tuberculous meningitis using enzyme-linked immunosorbent assay utilizing a 30,000-dalton native antigen of mycobacterium tuberculosis / _cJaime C. Montoya
520	3		_aAn enzyme-linked immunosorbent assay (ELISA) was estimated for the detection of lgG antibody in human cerebrospinal fluid (CSF) from patients with tuberculous meningitis to the 30,000-Da native antigen of Mycobacterium tuberculosis. The test was done on patients with bacteriologically confirmed and autopsy-proven tuberculous meningitis (8 cases), clinically presumptive cases of tuberculous neurologic disease (88 cases) and normal patients with neurologic disease (10 cases). The test was positive in 7 of the 8 cases of bacteriologically confirmed tuberculous meningitis (87.5%). ELISA was also positive in 67 of 100 cases of clinically presumptive tuberculous meningitis (67.00%). Overall sensitivity was found to be 68.51%. Specificity of ELISA was found to be 97.95% (96/98). The results show the potential use of ELISA as a rapid diagnosis test for tuberculous meningitis .
580			_aActa Medica Philippina, 2000 36 ( 1&2 ) pages 22-26
650		2	_aTuberculosis, Meningeal _xdiagnosis
650		2	_aEnzyme-Linked Immunosorbent Assay
650		2	_aMycobacterium tuberculosis
650		2	_aAntigens
942			_cJA
999			_c3473 _d3473