| 000 | 03089nam a22003737a 4500 | ||
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| 001 | D0001C000172 | ||
| 003 | DOH | ||
| 005 | 20210408141413.0 | ||
| 008 | 210408b ||||| |||| 00| 0 eng d | ||
| 245 | 0 | 0 |
_aSerology surveillance of SARS-CoV-2 antibodies among healthcare workers in COVID-19 designated facilities in Malaysia / _cYuan Liang Woon [and sixteen others] |
| 520 | 3 | _aBackground: Asymptomatic severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infections are well documented. Healthcare workers (HCW) are at increased risk of infection due to occupational exposure to infected patients. We aim to determine the prevalence of SARS-CoV-2 antibodies among HCW who did not come to medical attention. Methods: We prospectively recruited 400 HCW from the National Public Health Laboratory and two COVID-19 designated public hospitals in Klang Valley, Malaysia between 13/4/2020 and 12/5/2020. Quota sampling was used to ensure representativeness of HCW involved in direct and indirect patient care. All participants answered a self-administered questionnaire and blood samples were taken to test for SARS-CoV-2 antibodies by surrogate virus neutralization test. Findings: The study population comprised 154 (38.5%) nurses, 103 (25.8%) medical doctors, 47 (11.8%) laboratory technologists and others (23.9%). A majority (68.9%) reported exposure to SARS-CoV-2 in the past month within their respective workplaces. Adherence to personal protection equipment (PPE) guidelines and hand hygiene were good, ranging from 91-100% compliance. None (95% CI: 0, 0.0095) of the participants had SARS-CoV-2 antibodies detected, despite 182 (45.5%) reporting some symptoms one month prior to study recruitment. One hundred and fifteen (29%) of participants claimed to have had contact with known COVID-19 persons outside of their workplace. Interpretation: Zero seroprevalence among HCW suggests a low incidence of undiagnosed COVID-19 infection in our healthcare setting during the first local wave of SARS-CoV-2 infection. The occupational risk of SARS-CoV-2 transmission within healthcare facilities can be prevented by adherence to infection control measures and appropriate use of PPE. © 2021 The Author(s). | |
| 580 | _aLancet Reg Health West Pac. 2021 Apr 9: 100123 doi: 10.1016/j.lanwpc.2021.100123 | ||
| 650 | 2 | _aCOVID-19 Serological Testing | |
| 650 | 2 | _aHealth Personnel | |
| 700 | 1 | _aWoon, Yuan Liang | |
| 700 | 1 | _a Lee, Yee Leng | |
| 700 | 1 | _aChong, Yoong Min | |
| 700 | 1 | _aAyub, Nor Aliya | |
| 700 | 1 | _aKrishnabahawan, Swarna Lata | |
| 700 | 1 | _aLau, June Fei Wen | |
| 700 | 1 | _aSubramaniam-Kalianan, Ramani | |
| 700 | 1 | _aSam, I-Ching | |
| 700 | 1 | _aChan, Yoke Fun | |
| 700 | 1 | _aSevalingam, Raj Kumar | |
| 700 | 1 | _aRamli, Azura | |
| 700 | 1 | _aChuah, Chuan Huan | |
| 700 | 1 | _aMat-Hussin, Hani | |
| 700 | 1 | _aLeong, Chee Loon | |
| 700 | 1 | _aChidambaram, Suresh Kumar | |
| 700 | 1 | _aPeariasamy, Kalaiarasu M. | |
| 700 | 1 | _aGoh, Pik Pin | |
| 856 | _uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7982055/ | ||
| 942 | _cCV | ||
| 999 |
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