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_d686
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008 200521b ph ||||| |||| 00| 0 eng d
040 _aDOH
_cDOH
245 0 0 _aCorrelates of gonococcal infection and of antimicrobial-resistant neisseria gonorrhoeae among females sex workers, Republic of the Philippines /
_cJeffrey D. Klausner [and five others]
520 3 _aFrom 1994 to 1997, the proportion of Neisseria gonorrhoeae highly resistant to ciprofloxacin (MIC >/=4 microg/mL) increased substantially among female sex workers (FSWs) in the Philippines. Among 1499 Filipina FSWs, we evaluated factors associated with gonococcal infection and with gonococcal antimicrobial resistance. By multivariate analysis, gonococcal infection was associated with sex with a new client, self-prescribed prophylactic antimicrobial use, work in a brothel, and inconsistent condom use and was negatively associated with registration status and vaginal hygiene practices. Factors associated with ciprofloxacin-resistant gonococci included: marital status, living alone, duration of sex work, and clinic site. Further, gonococci highly resistant to ciprofloxacin were isolated from 10 (11.5%) of 87 FSWs reporting self-prescribed antimicrobial use versus 44 (3.4%) of 1295 reporting no antimicrobial use (P<.001). Self-prescribed prophylactic antimicrobial use and inconsistent condom use could be important factors in the continued emergence of gonococcal antimicrobial resistance in the Philippines.
_uhttps://pubmed.ncbi.nlm.nih.gov/9952388/
580 _aIn: Journal of Infectious Diseases, 1999 Vol. 179 (3) pages 729-33
650 2 _aAnti-Infective Agents
_xpharmacology
650 2 _aAnti-Infective Agents
_xtherapeutic use
650 2 _aCiprofloxacin
_xpharmacology
650 2 _aGonorrhea
_xdrug therapy
650 2 _aSexually Transmitted Diseases
_xepidemiology
653 _aSex Workers
700 1 _aKlausner, Jeffrey D.
700 1 _aAplasca, Mari-Rose
700 1 _aMesola, Virginia P.
700 1 _a Bolan, Gail
700 1 _aWhittington, W. L.
700 1 _aHolmes, King K.
856 _uhttps://academic.oup.com/jid/article/179/3/729/809506
942 _cJA