The pathology of spontaneous abortion : observations in sixty consecutive cases at the Philippine General Hospital / Edna May Lasap-Go, Jose Ma C. Avila

Contributor(s):

Subject(s):

Abortion, Spontaneous -- pathology

Abstract: Sixty consecutive curettage specimens from spontaneous abortions submitted at the Surgical Pathology Section of the Philippine General Hospital were examined for gross developmental disorders and microscopic developmental and inflammatory lesions. On gross examination, fourteen of the specimens showed intact chorionic sacs. One case showed a normal embryo (Groupl) and thirteen cases exhibited growth disorganized embryos (CD) divided as follows: three unembryonic chorionic sacs (GDI), nine nodular embryos (GD2) and one cylindrical embryo (GD3). Among the developmental lesions, hydropic villi were the most common (24 percent), followed by dysmorphic villi (22 percent), then villous trophoblastic hyperplasia (12 percent). Non-specific deciduitis was the most common inflammatory lesion (39 percent). Other inflammatory lesions observed were perivillous fibrin (38 percent), intervillositis (24 percent) and chronic villitis (4 percent). Many of the cases showed concurrences of these inflammatory and developmental lesions. This study has shown that gross and microscopic developmental lesions and inflammatory lesions are seen in cases of spontaneous abortions and warrant further investigations.

Hello from Record Display Customizations!

Tags from this library: No tags from this library for this title. Log in to add tags.

Average rating: 0.0 (0 votes)

Holdings
Cover image	Item type	Current library	Home library	Collection	Shelving location	Call number	Materials specified	Vol info	URL	Copy number	Status	Notes	Date due	Barcode	Item holds	Item hold queue priority	Course reserves
	Journal Article	DOH Central Library Electronic Resource Section				J000018 (Browse shelf(Opens below))					Available			D0001J000018

Sixty consecutive curettage specimens from spontaneous abortions submitted at the Surgical Pathology Section of the Philippine General Hospital were examined for gross developmental disorders and microscopic developmental and inflammatory lesions. On gross examination, fourteen of the specimens showed intact chorionic sacs. One case showed a normal embryo (Groupl) and thirteen cases exhibited growth disorganized embryos (CD) divided as follows: three unembryonic chorionic sacs (GDI), nine nodular embryos (GD2) and one cylindrical embryo (GD3). Among the developmental lesions, hydropic villi were the most common (24 percent), followed by dysmorphic villi (22 percent), then villous trophoblastic hyperplasia (12 percent). Non-specific deciduitis was the most common inflammatory lesion (39 percent). Other inflammatory lesions observed were perivillous fibrin (38 percent), intervillositis (24 percent) and chronic villitis (4 percent). Many of the cases showed concurrences of these inflammatory and developmental lesions. This study has shown that gross and microscopic developmental lesions and inflammatory lesions are seen in cases of spontaneous abortions and warrant further investigations.