Myocardial perfusion imaging using technetium 99m-tetrofosmin :
Myocardial perfusion imaging using technetium 99m-tetrofosmin : A comparative study with coronary angiography /
Josefina M. Lagunzad [and two others]
Results of resting and exercise tetrofosmin myocardial perfusion imaging of 54 patients (48 men and 6 women; mean age of 59) were reviewed and analyzed and compared with their respective coronary angiographic findings. Forty one patients with coronary artery disease (CAD) (50% luminal stenosis) had an abnormal myocardial scintigram. Four patients with significant CAD showed normal myocardial imaging. In one patient, the result of myocardial perfusion was equivocal. Six patients without significant CAD had normal perfusion imaging. Overall sensitivity, specificity and accuracy of tetrofosmin myocardial perfusion in the detection of significant CAD were 91%, 75% and 88% respectively. Positive predictive value was 95% while the negative predictive value was 60%. The localization of defects by tetrofosmin myocardial perfusion imaging in relation to the perfusion territories of stenosed vessels of 50% was achieved with 92% sensitivity, 50% specificity and 62% accuracy for the LAD, 87%, 59%, and 67% respectively for the Left Circumflex Artery and 89%, 58%, and 69% respectively for the RCA. Positive predictive values were 92%, 87%, and 89% for LAD, LCx, and RCA respectively, while negative predictive values were 30%, 59%, and 58%, respectively for LAD, LCx and RCA.
Makati Medical Center Proceedings, 1999 (13) pages 35-38
Exercise Test
Coronary Disease--physiopathology
Thallium Radioisotopes
Results of resting and exercise tetrofosmin myocardial perfusion imaging of 54 patients (48 men and 6 women; mean age of 59) were reviewed and analyzed and compared with their respective coronary angiographic findings. Forty one patients with coronary artery disease (CAD) (50% luminal stenosis) had an abnormal myocardial scintigram. Four patients with significant CAD showed normal myocardial imaging. In one patient, the result of myocardial perfusion was equivocal. Six patients without significant CAD had normal perfusion imaging. Overall sensitivity, specificity and accuracy of tetrofosmin myocardial perfusion in the detection of significant CAD were 91%, 75% and 88% respectively. Positive predictive value was 95% while the negative predictive value was 60%. The localization of defects by tetrofosmin myocardial perfusion imaging in relation to the perfusion territories of stenosed vessels of 50% was achieved with 92% sensitivity, 50% specificity and 62% accuracy for the LAD, 87%, 59%, and 67% respectively for the Left Circumflex Artery and 89%, 58%, and 69% respectively for the RCA. Positive predictive values were 92%, 87%, and 89% for LAD, LCx, and RCA respectively, while negative predictive values were 30%, 59%, and 58%, respectively for LAD, LCx and RCA.
Makati Medical Center Proceedings, 1999 (13) pages 35-38
Exercise Test
Coronary Disease--physiopathology
Thallium Radioisotopes