A case study evaluating the risk of infection from Middle Eastern Respiratory Syndrome Coronavirus (MERS-CoV) in a hospital setting through bioaerosols / (Record no. 1796)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02997nam a22003857a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | DOH |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20201123114606.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 201123b ||||| |||| 00| 0 eng d |
| 245 00 - TITLE STATEMENT | |
| Title | A case study evaluating the risk of infection from Middle Eastern Respiratory Syndrome Coronavirus (MERS-CoV) in a hospital setting through bioaerosols / |
| Statement of responsibility, etc. | Umesh Adhikari [and eleven others] |
| 520 3# - SUMMARY, ETC. | |
| Summary, etc. | Middle Eastern respiratory syndrome, an emerging viral infection with a global case fatality rate of 35.5%, caused major outbreaks first in 2012 and 2015, though new cases are continuously reported around the world. Transmission is believed to mainly occur in healthcare settings through aerosolized particles. This study uses Quantitative Microbial Risk Assessment to develop a generalizable model that can assist with interpreting reported outbreak data or predict risk of infection with or without the recommended strategies. The exposure scenario includes a single index patient emitting virus-containing aerosols into the air by coughing, leading to short- and long-range airborne exposures for other patients in the same room, nurses, healthcare workers, and family visitors. Aerosol transport modeling was coupled with Monte Carlo simulation to evaluate the risk of MERS illness for the exposed population. Results from a typical scenario show the daily mean risk of infection to be the highest for the nurses and healthcare workers (8.49 × 10-4 and 7.91 × 10-4 , respectively), and the lowest for family visitors and patients staying in the same room (3.12 × 10-4 and 1.29 × 10-4 , respectively). Sensitivity analysis indicates that more than 90% of the uncertainty in the risk characterization is due to the viral concentration in saliva. Assessment of risk interventions showed that respiratory masks were found to have a greater effect in reducing the risks for all the groups evaluated (>90% risk reduction), while increasing the air exchange was effective for the other patients in the same room only (up to 58% risk reduction). |
| 580 ## - LINKING ENTRY COMPLEXITY NOTE | |
| Linking entry complexity note | In: Risk Analysis 2019 vol. 39 (12) pages: 2608-2624. <br/>doi: 10.1111/risa.13389. Epub 2019 Sep 16.<br/><br/> |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Aerosols |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Air Microbiology |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Coronavirus Infections |
| General subdivision | epidemiology |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Coronavirus Infections |
| General subdivision | transmission |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cross Infection |
| General subdivision | prevention and control |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Masks |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Middle East Respiratory Syndrome Coronavirus |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Risk Management |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Adhikari, Umesh |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Chabrelie, Alexandre |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Weir, Mark |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Boehnke, Kevin |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | McKenzie, Erica |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Ikner, Luisa |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Wang, Meng |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Wang, Qing |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Young, Kyana |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Haas, Charles N |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Rose, Joan |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mitchell, Jade |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7169172/pdf/RISA-39-2608.pdf">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7169172/pdf/RISA-39-2608.pdf</a> |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | COVID 19 Resource |
| 999 ## - | |
| -- | 1796 |
| -- | 1796 |
| Withdrawn status | Lost status | Damaged status | Not for loan | Home library | Current library | Shelving location | Date acquired | Total Checkouts | Full call number | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| DOH Central Library | DOH Central Library | Electronic Resource Section | 11/23/2020 | COVID-19-000063 | D0001C000063 | 11/23/2020 | 11/23/2020 | COVID 19 Resource |