Correlation study between erythrocyte acetylcholinesterase activity, serum malondialdehyde and insulin sensitivity in agricultural workers and non-agricultural workers in Nat-Kan Village, Magway Township / (Record no. 1870)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02378nam a22002057a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | DOH |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20201127105647.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 201127b ||||| |||| 00| 0 eng d |
| 245 00 - TITLE STATEMENT | |
| Title | Correlation study between erythrocyte acetylcholinesterase activity, serum malondialdehyde and insulin sensitivity in agricultural workers and non-agricultural workers in Nat-Kan Village, Magway Township / |
| Statement of responsibility, etc. | Mya Pwint Phyu [and four others] |
| 520 3# - SUMMARY, ETC. | |
| Summary, etc. | Objective. This study determined the correlation between erythrocyte acetylcholinesterase (AChE) activity, serum malondialdehyde (MDA) and insulin sensitivity in agricultural workers and non-agricultural workers.<br/><br/>Methodology. The cross-sectional comparative study was undertaken in 45 agricultural and 45 non-agricultural workers from Nat-Kan Village, Magway Township. Erythrocyte acetylcholinesterase activity and serum malondialdehyde were measured by spectrophotometric method. Insulin sensitivity was calculated by homeostasis model assessment (HOMA-IR).<br/><br/>Results. Mean erythrocyte AChE activity was significantly lower in agricultural (3553.99 IU/L) compared with nonagricultural workers (4432.68 IU/L) (p<0.001). A significant high level of mean serum MDA was observed in agricultural workers (0.74 versus 0.28 μmol/L, p<0.001). Median HOMA-IR value was significantly higher in agricultural (2.74) than that of non-agricultural workers (2.28) (p<0.05). The risk of insulin resistance was 2.8 times greater in agricultural workers than non-agricultural workers (OR 2.8, 95% CI, 1.18 to 6.72). Erythrocyte AChE activity had weak negative correlation with serum MDA level (r=-0.357, p<0.001) and HOMA-IR (ρ= 0.305, p<0.05). There was a significant but weak positive correlation between serum MDA level and HOMA-IR (ρ=0.355, p<0.001).<br/><br/>Conclusion. Organophosphate pesticide exposure lowered erythrocyte AChE activity and increased oxidative stress. Oxidative stress is partly attributed to the development of insulin resistance. |
| 580 ## - LINKING ENTRY COMPLEXITY NOTE | |
| Linking entry complexity note | In: Journal of the ASEAN Federation of Endocrine Societies, 2020 Vol. 35 (1) pages: 85-92 |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Phyu, Mya Pwint |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hlain, Zarchi Theint Theint |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Zaw, Thurein |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Htway, Soe Minn |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Sein, Mya Thanda |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://asean-endocrinejournal.org/index.php/JAFES/article/view/645/1289">https://asean-endocrinejournal.org/index.php/JAFES/article/view/645/1289</a> |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | Journal Article |
| 999 ## - | |
| -- | 1870 |
| -- | 1870 |
| Withdrawn status | Lost status | Damaged status | Not for loan | Home library | Current library | Shelving location | Date acquired | Total Checkouts | Full call number | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| DOH Central Library | DOH Central Library | Electronic Resource Section | 11/27/2020 | E000158 | D0001E000158 | 11/27/2020 | 11/27/2020 | Journal Article |