Cost-effectiveness analysis of imidapril compared to metoprolol in the treatment of stage 1 essential hypertension among Filipino patients seen at the Philippine General Hospital / (Record no. 2804)

MARC details
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fixed length control field 02084nam a22002057a 4500
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control field DOH
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control field 20210211113836.0
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Title Cost-effectiveness analysis of imidapril compared to metoprolol in the treatment of stage 1 essential hypertension among Filipino patients seen at the Philippine General Hospital /
Statement of responsibility, etc. He Wentian [two others]
520 3# - SUMMARY, ETC.
Summary, etc. OBJECTIVE: To evaluate the cost-effectiveness of imidapril versus metoprolol as monotherapy in Filipino patients with Stage 1 essential hypertension.<br/><br/><br/>STUDY DESIGN: Cost-effectiveness analysis from the perspective of the health care payer.<br/><br/><br/>METHOD: Medical records of 94 out-patients aged 40-70 years old, with Stage 1 essential hypertension and follow-up treatment of 3 months at the Philippine General Hospital were reviewed. Effectiveness of each drug was based on: 1) percentage of patients achieving target blood pressure (< 140 / 90 mmHg); and 2) mean reduction of systolic and diastolic blood pressure. Cost-effectiveness of each drug was evaluated using the criteria of cost-effectiveness ratio (CER) and the incremental cost-effectiveness ratio (ICER).<br/><br/><br/>RESULTS: The mean cost of treatment with metoprolol was significantly lower than imidapril. However, treatment with imidapril resulted in a statistically significantly better blood pressure control compared to metoprolol; 77 percent of those given imidapril achieved the target BP vs 56 percent for metoprolol (p=0.03). CER and the ICER showed that 3-months treatment with metoprolol is more cost-effective than the use of imidapril.<br/><br/><br/>CONCLUSION: Use of metoprolol over a 3-month period is more cost-effective than imidapril in the treatment of Filipino patients with Stage 1 essential hypertension.
580 ## - LINKING ENTRY COMPLEXITY NOTE
Linking entry complexity note In: Acta Medica Philippina, 2006 vol. 40 (1) pages: 29-36
650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Metoprolol
650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Hypertension
General subdivision therapy
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Imidapril
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Wentian, He
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Personal name Jimeno, Cecilia A.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Panelo, Carlo Irwin A.
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Koha item type Journal Article
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-- 2804
Holdings
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    National Library of Medicine     DOH Central Library DOH Central Library Electronic Resource Section 02/11/2021   J000020 D0001J000020 02/11/2021 02/11/2021 Journal Article