The effect of Swietenia mahogani (Mahogany) seed extract on indomethacin-induced gastric ulcers in female sprague-dawley rats / (Record no. 3554)

MARC details
000 -LEADER
fixed length control field 01993nam a22003137a 4500
003 - CONTROL NUMBER IDENTIFIER
control field DOH
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20210316163123.0
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fixed length control field 210316b ||||| |||| 00| 0 eng d
245 04 - TITLE STATEMENT
Title The effect of Swietenia mahogani (Mahogany) seed extract on indomethacin-induced gastric ulcers in female sprague-dawley rats /
Statement of responsibility, etc. A. Rodriguez [and eleven others]
520 3# - SUMMARY, ETC.
Summary, etc. Swietenia mahogani (mahogany) has been reported to have medicinal uses, such as treatment for hypertension, cancer, amoebiasis, chest pains and intestinal parasitism. This study examined the effect of mahogany seed extracts on indomethacin-induced gastric ulcers in female Sprague-Dawley rats. Forty five 2-3 month-old rats weighing 150-200 g were randomly assigned into 5 treatment groups, namely: [1] 5% polyvinylpyrrolidone (PVP), [2] misoprostol (144ug/kg BW), [3] 0.14g mahogany seed extract/kg BW, [4] 0.28 g mahogany seed extract/kg BW, and [5]0.57 g mahogany seed extract/kg BW. After three days of administration of treatments using gavage method, the rats were sacrificed, and their stomachs graded grossly using Bests Ulcer Staging Index. Histopathologic grading was also conducted. At the doses utilized in this study, mahogany seed extract was found to have a potential effect on the healing of gastric ulcers. It is speculated that this effect can be attributed to the phospholipid and long chain unsaturated fatty acid content of mahogany seeds. Further studies are recommended to verify these findings.
580 ## - LINKING ENTRY COMPLEXITY NOTE
Linking entry complexity note Acta Medica Philippina,1997 33 ( 3 ) pages 127-139
650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Stomach Ulcer
650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Meliaceae
653 ## - INDEX TERM--UNCONTROLLED
Uncontrolled term Mahogany
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Rodriguez, A
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Bacsal, K
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Personal name Panganiban, C
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Montalban, J
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Manzanilla, H
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Javillo, J
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Yap, S
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Espina, S
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Talip, B
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Diaz, I
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Sumpaico, C
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Chavez, L
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Journal Article
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    National Library of Medicine     DOH Central Library DOH Central Library Electronic Resource Section 03/16/2021   J000165 D0001J000165 03/16/2021 03/16/2021 Journal Article