Clostridium difficile and entamoeba histolytica infections in patients with colitis in the Philippines / (Record no. 783)

MARC details
000 -LEADER
fixed length control field 02778nam a22003137a 4500
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control field D0001E000041
003 - CONTROL NUMBER IDENTIFIER
control field DOH
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20200806155506.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 200527b ph ||||| |||| 00| 0 eng d
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Transcribing agency DOH
245 00 - TITLE STATEMENT
Title Clostridium difficile and entamoeba histolytica infections in patients with colitis in the Philippines /
Statement of responsibility, etc. Cirle Alcantara Warren [and five others]
520 3# - SUMMARY, ETC.
Summary, etc. Amoebiasis is a common cause of non-specific colitis in the Philippines. The prevalence of Clostridium difficile infection with colitis is unknown. Empiric use of metronidazole for colitis treatment is widely practiced. We investigated the association of C. difficile or Entamoeba histolytica infection with endoscopically/histopathologically proven colitis among adults in the Philippines. Two hundred and ten patients undergoing colonoscopy were enrolled. Demographic and clinical data were reviewed. Stool specimens were assayed for C. difficile and E. histolytica by ELISA. Microscopy was performed. The mean age of the patients was 53 y (range: 19-88 y) and 53% were male. Colitis was diagnosed in 39 of 205 patients. Clostridium difficile, E. histolytica and parasites were seen in 17 (43.6%), 10 (25.6%) and 11 (28.2%), respectively, of patients with colitis compared with 36 (21.7%; p=0.005), 13 (7.8%; p=0.001) and 56 (33.7%; p=0.51), respectively, of those without colitis. Diarrhoea and antibiotic intake history were significantly more common among patients with colitis than those without (43.6% and 20.5% vs 18.1% and 5.4%; p=0.001 and p=0.006, respectively). The mean duration of diarrhoea was 2.53 d shorter among patients with colitis. The most frequent antibiotics taken were fluoroquinolones and metronidazole (50% and 40% of antibiotic courses, respectively, in patients with colitis). This study suggests that C. difficile infection is common and might be overlooked in settings where amoebiasis and intestinal parasitism are endemic.
Uniform Resource Identifier <a href="https://pubmed.ncbi.nlm.nih.gov/22657531/">https://pubmed.ncbi.nlm.nih.gov/22657531/</a>
580 ## - LINKING ENTRY COMPLEXITY NOTE
Linking entry complexity note In: Transactions of the Royal Society of Tropical Medicine and Hygiene, 2012 vol. 106 (7) pages 424-428.
650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Anti-Infective Agents
General subdivision therapeutic use
650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Clostridium Infections
General subdivision drug therapy
650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Clostridium Infections
General subdivision epidemiology
650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Clostridium Infections
General subdivision microbiology
650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Colitis
General subdivision drug therapy
650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Entamoebiasis
General subdivision drug therapy
650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Metronidazole
General subdivision therapeutic use
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Warrena, Cirle Alcantara
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Labiob, Eternity
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Desturac, Raul
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Sevilleja, Jesus Emmanuel
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Jamiasb, Jade D.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Daezb, Ma. Lourdes O.
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Uniform Resource Identifier <a href="https://academic.oup.com/trstmh/article-lookup/doi/10.1016/j.trstmh.2012.04.005">https://academic.oup.com/trstmh/article-lookup/doi/10.1016/j.trstmh.2012.04.005</a>
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Journal Article

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