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Late-onset neonatal septicemia due to coagulase-negative staphylococcus / Robert Dennis J. Garcia , Marie Arlene A. Esteves-Genio

Contributor(s): Subject(s): Abstract: This retrospective study of 37 episodes of Coagulase-negative Staphylococcus (CONS) sepsis in 34 neonates in a level-3 nursery over a period of nineteen months from January, 1996 to July, 1997 showed CONS to be a late-onset pathogen, being cultured from blood at a mean of 11.3 days. Prolonged intravenous cannulation (mean = 36 days) and prolonged hospital stay (mean = 43.8 days) were common. Decreased activity, jaundice, and apnea were the most common clinical manifestations, but CONS sepsis was not accompanied by specific nor prominent symptoms, so that a high index of suspicion is necessary. Hyperbilirubinemia, thrombocytopenia, hypoglycemia, and positive CRP were the common laboratory findings seen, but only in a minority of neonates. Mortality was low.
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Journal Article DOH Central Library Electronic Resource Section J000666 (Browse shelf(Opens below)) Available D0001J000666

This retrospective study of 37 episodes of Coagulase-negative Staphylococcus (CONS) sepsis in 34 neonates in a level-3 nursery over a period of nineteen months from January, 1996 to July, 1997 showed CONS to be a late-onset pathogen, being cultured from blood at a mean of 11.3 days. Prolonged intravenous cannulation (mean = 36 days) and prolonged hospital stay (mean = 43.8 days) were common. Decreased activity, jaundice, and apnea were the most common clinical manifestations, but CONS sepsis was not accompanied by specific nor prominent symptoms, so that a high index of suspicion is necessary. Hyperbilirubinemia, thrombocytopenia, hypoglycemia, and positive CRP were the common laboratory findings seen, but only in a minority of neonates. Mortality was low.


Makati Medical Center Proceedings, 1999 (13) pages 109-112

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